• Core genome conservation of Staphylococcus haemolyticus limits sequence based population structure analysis 

      Cavanagh, Jorunn Pauline; Klingenberg, Claus Andreas; Hanssen, Anne-Merethe; Aarag, Elizabeth; Francois, Patrice; Schrenzel, Jaques; Flægstad, Trond; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      The notoriously multi-resistant Staphylococcus haemolyticus is an emerging pathogen causing serious infections in immunocompromised patients. Defining the population structure is important to detect outbreaks and spread of antimicrobial resistant clones. Currently, the standard typing technique is pulsed-field gel electrophoresis (PFGE). In this study we describe novel molecular typing schemes for ...
    • Host and microbe determinants that may influence the success of S. aureus colonization 

      Johannessen, Mona; Sollid, Johanna U Ericson; Hanssen, Anne-Merethe (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Staphylococcus aureus may cause serious skin and soft tissue infections, deep abscesses, endocarditis, osteomyelitis, pneumonia, and sepsis. S. aureus persistently colonizes 25–30% of the adult human population, and S. aureus carriers have an increased risk for infections caused by the bacterium. The major site of colonization is the nose, i.e., the vestibulum nasi, which is covered with ordinary ...
    • The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells 

      Askarian, Fatemeh; Ajayi, Clement; Hanssen, Anne-Merethe; Van Sorge, Nina M.; Pettersen, Ingvild; Diep, Dzung Bao; Sollid, Johanna U. Ericson; Johannessen, Mona (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-29)
      <i>Staphylococcus aureus</i> is known as a frequent colonizer of the skin and mucosa. Among bacterial factors involved in colonization are adhesins such as the microbial surface components recognizing adhesive matrix molecules (MSCRAMMs). Serine aspartate repeat containing protein D (SdrD) is involved in adhesion to human squamous cells isolated from the nose. Here, we identify Desmoglein 1 ...
    • Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers 

      Hanssen, Anne-Merethe; Kindlund, Bert; Stenklev, Niels Christian; Furberg, Anne-Sofie; Fismen, Silje; Olsen, Renate Slind; Johannessen, Mona; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-04-05)
      <p><b>Background:</b> Colonization of the body is an important step in Staphylococcus aureus infection. S. aureus colonizes skin and mucous membranes in humans and several animal species. One important ecological niche of S. aureus is the anterior nares. More than 60% of the S. aureus in the nose are found in vestibulum nasi. Our aim was to describe the localization of S. aureus in nasal tissue ...
    • A Look into the Melting Pot: The mecC-Harboring Region Is a Recombination Hot Spot in Staphylococcus stepanovicii 

      Semmler, Torsten; Harrison, Ewan M.; Lübke-Becker, Antina; Ulrich, Rainer G.; Wieler, Lothar H.; Guenther, Sebastian; Stamm, Ivonne; Hanssen, Anne-Merethe; Holmes, Mark A.; Vincze, Szilvia; Walther, Birgit (Journal article; Tidsskriftartikkel, 2016-01-22)
      INTRODUCTION Horizontal gene transfer (HGT) is an important driver for resistance- and virulence factor accumulation in pathogenic bacteria such as Staphylococcus aureus. METHODS Here, we have investigated the downstream region of the bacterial chromosomal attachment site (attB) for the staphylococcal cassette chromosome mec (SCCmec) element of a commensal mecC-positive Staphylococcus ...